Clinical Application of Urinary Hormones

Cortisol and Cortisone

 Addison’s disease
 Adrenal fatigue (pre and post ACTH)
 Synthetic corticosteroid toxicity
 Altered expression of 11–hydroxy steroid dehydrogenases
 Hypertension (salt-sensitive)
 Apparent mineralocorticoid excess
 Emotional stress
 Bio-Identical hormone replacement
 Cushing’s syndrome

Estrogens and Pregnanediol

 Perimenopause
 Menopause
 Bio-Identical hormone replacement
 Liver detoxification
 Estrogen “dominance”

Androgens

 Andropause
 Decreased libido
 Bio-Identical hormone replacement

Aldosterone

 Mineralocorticoid excess

Cortisol Test Indications

 Monitoring bio-identical hormone replacement
 Adrenal insufficiency (tested before and after ACTH administration)
 Breast lesions
 Anorexia nervosa
 Hypertension
 Emotional stress
 Idiopathic hirsutism
 Carcinoma
 Endocrine disorders
 Chronic fatigue syndrome
 Fibromyalgia
 Rheumatoid arthritis
 5-alpha reductase deficiency
 Monitoring liver detoxification

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