PLUS Profile

The PLUS profile is our most popular 24-hour urine profile and provides both broad and in-depth evaluation of hormone balance and function. This panel measures estrogens and clinically relevant estrogen metabolites, which allow for assessment of cancer risk factors and detoxification pathways. Pregnanediol assays progesterone activity in the body. DHEA, testosterone and their metabolites provide a detailed assessment of androgen function. Cortisol, cortisone, aldosterone and their metabolites provide an industry-leading evaluation of adrenal health. Urinary free T3 and free T4 provide a sensitive gauge of thyroid hormone status. The Plus profile also calculates 5a – Reductase and 11β-Hydroxysteroid Dehydrogenase II enzyme activity. 5a – Reductase is an important enzyme that governs androgen metabolism and is associated with insulin resistance and other conditions. 11β-HSD determines the balance between cortisol and cortisone. Overall, the Plus profile provides an ideal method for assessing hormonal balance and for monitoring bio-identical hormone replacement therapy.